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Antibiotic-resistant Klebsiella pneumoniae and Escherichia coli high-risk clones and an IncFII(k) mosaic plasmid hosting Tn1 (blaTEM-4) in isolates from 1990 to 2004

dc.contributor.authorRodríguez, Irene
dc.contributor.authorNovais, Ângela
dc.contributor.authorLira, Felipe
dc.contributor.authorValverde, Aránzazu
dc.contributor.authorCurião, Tânia
dc.contributor.authorMartínez, José Luis
dc.contributor.authorBaquero, Fernando
dc.contributor.authorCantón, Rafael
dc.contributor.authorCoque, Teresa M
dc.date.accessioned2023-06-18T06:57:28Z
dc.date.available2023-06-18T06:57:28Z
dc.date.issued2015-05
dc.description.abstractWe describe the genetic background of bla(TEM-4) and the complete sequence of pRYC11::bla(TEM-4), a mosaic plasmid that is highly similar to pKpQIL-like variants, predominant among TEM-4 producers in a Spanish hospital (1990 to 2004), which belong to Klebsiella pneumoniae and Escherichia coli high-risk clones responsible for the current spread of different antibiotic resistance genes. Predominant populations of plasmids and host adapted clonal lineages seem to have greatly contributed to the spread of resistance to extended-spectrum cephalosporins.
dc.description.facultyCentro de Vigilancia Sanitaria Veterinaria (VISAVET)
dc.description.refereedTRUE
dc.description.sponsorshipUnión Europea. FP7
dc.description.sponsorshipInstituto de Salud Carlos III
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/39627
dc.identifier.doi10.1128/AAC.00296-15
dc.identifier.issn1098-6596
dc.identifier.officialurlhttp://aac.asm.org/content/59/5/2904
dc.identifier.urihttps://hdl.handle.net/20.500.14352/24668
dc.issue.number5
dc.journal.titleAntimicrobial agents and chemotherapy
dc.language.isoeng
dc.page.final8
dc.page.initial2904
dc.publisherAmerican Society for Microbiology
dc.relation.projectIDEVOTAR (282004)
dc.relation.projectIDR-GNOSIS (282512)
dc.relation.projectID(PI12-01581)
dc.relation.projectIDCIBER CB06/02/0053
dc.rights.accessRightsrestricted access
dc.subject.ucmVeterinaria
dc.subject.unesco3109 Ciencias Veterinarias
dc.titleAntibiotic-resistant Klebsiella pneumoniae and Escherichia coli high-risk clones and an IncFII(k) mosaic plasmid hosting Tn1 (blaTEM-4) in isolates from 1990 to 2004
dc.typejournal article
dc.volume.number59
dspace.entity.typePublication

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