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Mesoporous Silica Nanoparticles for Drug Delivery: Current Insights

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dc.contributor.authorVallet Regí, María Dulce Nombre
dc.contributor.authorColilla Nieto, Montserrat
dc.contributor.authorIzquierdo Barba, Isabel
dc.contributor.authorManzano García, Miguel
dc.date.accessioned2023-06-17T22:16:36Z
dc.date.available2023-06-17T22:16:36Z
dc.date.issued2017-12-25
dc.descriptionRESEARCHER ID M-3378-2014 (María Vallet Regí) ORCID 0000-0002-6104-4889 (María Vallet Regí) RESEARCHER ID N-4628-2014 (Montse Colilla Nieto) RESEARCHER ID M-9921-2014 (Isabel Izquierdo Barba) ORCID 0000-0002-4139-4646 (Isabel Izquierdo Barba) ORCID 0000-0003-1961-4160 (Montse Colilla Nieto) RESEARCHER ID K-3719-2014 (Miguel Manzano García) ORCID 0000-0001-6238-6111 (Miguel Manzano García)
dc.description.abstractThis manuscript reviews the recent progress on mesoporous silica nanoparticles as drug delivery systems. Their intrinsic structural, textural and chemical features permit to design versatile multifunctional nanosystems with the capability to target the diseased tissue and release the cargo on demand upon exposition to internal or external stimuli. The degradation rate of these nanocarriers in diverse physiological fluids is overviewed obeying their significance for their potential translation towards clinical applications. To conclude, the balance between the benefits and downsides of this revolutionary nanotechnological tool is also discussed.
dc.description.departmentDepto. de Química en Ciencias Farmacéuticas
dc.description.facultyFac. de Farmacia
dc.description.refereedTRUE
dc.description.sponsorshipUnión Europea. H2020
dc.description.sponsorshipMinisterio de Economía y Competitividad (MINECO)
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/45935
dc.identifier.doi10.3390/molecules23010047
dc.identifier.issn1420-3049
dc.identifier.officialurlhttps://doi.org/10.3390/molecules23010047
dc.identifier.relatedurlhttp://www.ucm.es/valletregigroup
dc.identifier.relatedurlhttps://www.mdpi.com/1420-3049/23/1/47
dc.identifier.urihttps://hdl.handle.net/20.500.14352/18309
dc.issue.number1
dc.journal.titleMOLECULES
dc.language.isoeng
dc.page.initial47
dc.publisherMDPI
dc.relation.projectIDVERDI (694160)
dc.relation.projectID(MAT2015-64831-R)
dc.rightsAtribución 3.0 España
dc.rights.accessRightsopen access
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/es/
dc.subject.cdu546
dc.subject.cdu615.46
dc.subject.keywordmesoporous silica nanoparticles
dc.subject.keywordmultifunctional nanosystem
dc.subject.keywordselective targeting
dc.subject.keywordstimuliresponsive drug delivery
dc.subject.keywordin vitro degradation
dc.subject.keywordbenefits and downsides
dc.subject.keywordclinical translation
dc.subject.keywordbiosafety
dc.subject.ucmMateriales
dc.subject.ucmQuímica inorgánica (Química)
dc.subject.unesco3312 Tecnología de Materiales
dc.subject.unesco2303 Química Inorgánica
dc.titleMesoporous Silica Nanoparticles for Drug Delivery: Current Insights
dc.typejournal article
dc.volume.number23
dspace.entity.typePublication
relation.isAuthorOfPublication791023b8-2531-44eb-ba01-56e3b7caa0cb
relation.isAuthorOfPublication449a114d-e3bf-4d4c-81c5-2b0c5f050b9d
relation.isAuthorOfPublicationee9272a2-db11-4efb-97f8-7ce1a18ad55e
relation.isAuthorOfPublication2a7febe9-6dd2-4117-aa12-552e54c12bd3
relation.isAuthorOfPublication.latestForDiscovery2a7febe9-6dd2-4117-aa12-552e54c12bd3

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