Understanding In Vivo Chromatic Aberrations in Pseudophakic Eyes Using on Bench and Computational Approaches

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dc.contributor.authorViñas Peña, María
dc.contributor.authorCastro Arribas, Alberto, de
dc.contributor.authorDorronsoro Díaz, Carlos
dc.contributor.authorGonzález Ramos, Ana María
dc.contributor.authorRedzovic, Suad
dc.contributor.authorWillet, Nicolas
dc.contributor.authorGarzón Jiménez, Nuria
dc.contributor.authorMarcos Celestino, Susana
dc.date.accessioned2023-06-22T11:24:35Z
dc.date.available2023-06-22T11:24:35Z
dc.date.issued2022-03-30
dc.description.abstractDiffractive multifocal intraocular lenses (IOLs) modulate chromatic aberration and reduce it at certain distances due to interactions between the refractive and diffractive chromatic components. However, the extent to which computer modeling and on bench measurements of IOL chromatic aberration translate to chromatic aberration in patients implanted with these multifocal IOLs (MIOLs) is not yet fully understood. In this study, we compare the chromatic difference of focus and longitudinal chromatic aberrations in pseudophakic patients implanted with different IOL designs (monofocal and trifocal IOLs) and materials (hydrophobic and hydrophilic), and compared them with predictions from computer eye models and on bench measurements with the same IOLs. Patient data consisted of results from 63 pseudophakic eyes reported in four different studies and obtained psychophysically in the visual testing channel of a custom-developed polychromatic adaptive optics system. Computational predictions were obtained using ray tracing on computer eye models, and modulation transfer function (MTF) on bench measurements on physical eye models. We found that LCA (in vivo/simulated) for far vision was 1.37 ± 0.08 D/1.19 D for monofocal hydrophobic, 1.21 ± 0.08 D/0.88 D for monofocal hydrophilic, 0.99 ± 0.06 D/1.19 D for MIOL hydrophobic, and 0.82 ± 0.05 D/0.88 D for MIOL hydrophilic. For intermediate and near vision, LCA (in vivo/simulated) was 0.67 ± 0.10 D/0.75 D and 0.23 ± 0.08 D/0.19 D for MIOL hydrophobic and 0.27 ± 0.15 D/0.38 D and 0.15 ± 0.15 D/−0.13 D for MIOL hydrophilic, respectively. In conclusion, computational ray tracing and on bench measurements allowed for evaluating in vivo chromatic aberration with different materials and designs for multifocal diffractive intraocular lenses.
dc.description.departmentDepto. de Optometría y Visión
dc.description.facultyFac. de Óptica y Optometría
dc.description.refereedTRUE
dc.description.sponsorshipEurepean Research Council
dc.description.sponsorshipGobierno de España
dc.description.sponsorshipPhyIOL (Liege, Belgium)
dc.description.sponsorshipNational Eye Institute (NEI)
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/78718
dc.identifier.doi10.3390/photonics9040226
dc.identifier.issn2304-6732
dc.identifier.officialurlhttps://doi.org/10.3390/photonics9040226
dc.identifier.relatedurlhttps://www.mdpi.com/2304-6732/9/4/226
dc.identifier.urihttps://hdl.handle.net/20.500.14352/72390
dc.issue.number4
dc.journal.titlePhotonics
dc.language.isoeng
dc.page.initial226
dc.publisherMDPI
dc.relation.projectIDERC-2011-AdG-294099
dc.relation.projectIDH2020-MSCA-IF-GF-2019-MYOMICRO-893557
dc.relation.projectIDFIS2017-84753
dc.relation.projectIDPID2020-115191RB-I00
dc.relation.projectIDEY001319-46
dc.rightsAtribución 3.0 España
dc.rights.accessRightsopen access
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/es/
dc.subject.cdu535.313.6
dc.subject.cdu617.7-086
dc.subject.keywordchromatic aberration
dc.subject.keywordpolychromatic optical quality
dc.subject.keywordpseudophakic eye
dc.subject.keywordintraocular lenses
dc.subject.keywordmultifocal designs
dc.subject.keywordvisual simulation
dc.subject.keyworddiffractive designs
dc.subject.ucmÓptica y optometría
dc.subject.unesco2209 Óptica
dc.titleUnderstanding In Vivo Chromatic Aberrations in Pseudophakic Eyes Using on Bench and Computational Approaches
dc.typejournal article
dc.volume.number9
dspace.entity.typePublication
relation.isAuthorOfPublication367ce491-287f-4b2a-ba6a-870a393c5609
relation.isAuthorOfPublication.latestForDiscovery367ce491-287f-4b2a-ba6a-870a393c5609
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