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A mathematical model of blood coagulation induced by activation sources

dc.contributor.authorGuria, G. T.
dc.contributor.authorHerrero, Miguel A.
dc.contributor.authorZlobina, K. E.
dc.date.accessioned2023-06-20T00:15:26Z
dc.date.available2023-06-20T00:15:26Z
dc.date.issued2009-09
dc.description.abstractIn this work a mathematical model for blood coagulation induced by an activator source is presented. Blood coagulation is viewed as a process resulting in fibrin polymerization, which is considered as the first step towards thrombi formation. We derive and study a system for the first moments of the polymer concentrations and the activating variables. Analysis of this last model allows us to identify parameter regions which could lead to thrombi formation, both in homeostatic and pathological situations.
dc.description.departmentDepto. de Análisis Matemático y Matemática Aplicada
dc.description.facultyFac. de Ciencias Matemáticas
dc.description.refereedTRUE
dc.description.sponsorshipEuropean Contract
dc.description.sponsorshipUniversidad Complutense Accion Especial
dc.description.sponsorshipJunta de Andalucia Project
dc.description.sponsorshipRussian Foundation for Basic Recearch Project
dc.description.sponsorshipInternational Science and Technology Center
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/16181
dc.identifier.doi10.3934/dcds.2009.25.175
dc.identifier.issn1078-0947
dc.identifier.officialurlhttp://www.aimsciences.org/journals/pdfs.jsp?paperID=4275&mode=full
dc.identifier.relatedurlhttp://www.aimsciences.org
dc.identifier.urihttps://hdl.handle.net/20.500.14352/42281
dc.issue.number1
dc.journal.titleDiscrete and Continuous Dynamical Systems. Series A.
dc.language.isoeng
dc.page.final194
dc.page.initial175
dc.publisherAmerican Institute of Mathematical Sciences
dc.relation.projectIDMRTN-CT-2004-503361
dc.relation.projectIDAE10/07-15449
dc.relation.projectIDE-1268
dc.relation.projectID07-04-01523a
dc.relation.projectID3744
dc.rights.accessRightsrestricted access
dc.subject.cdu519.87
dc.subject.cdu612.115
dc.subject.cdu616.15-005.6
dc.subject.keywordAggregation-fragmentation equations
dc.subject.keywordactivator-inhibitor systems
dc.subject.keywordfibrin polymerization
dc.subject.keywordblood coagulation
dc.subject.keywordsol-gel transition
dc.subject.keywordpolymerization
dc.subject.keywordthrombosis
dc.subject.keywordequations
dc.subject.keywordkinetics
dc.subject.keywordgelation
dc.subject.keywordcancer
dc.subject.keywordflow
dc.subject.ucmHematología
dc.subject.ucmInvestigación operativa (Matemáticas)
dc.subject.unesco3205.04 Hematología
dc.subject.unesco1207 Investigación Operativa
dc.titleA mathematical model of blood coagulation induced by activation sources
dc.typejournal article
dc.volume.number25
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