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Wire Myography to Study Vascular Tone and Vascular Structure of Isolated Mouse Arteries

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dc.book.titleMethods in Mouse Atherosclerosis
dc.contributor.authorDel Campo Milán, Lara
dc.contributor.authorFerrer, Mercedes
dc.date.accessioned2024-01-30T13:24:24Z
dc.date.available2024-01-30T13:24:24Z
dc.date.issued2015-10-01
dc.description.abstractAtherosclerosis is characterized by endothelial dysfunction and alterations in vascular reactivity, which can be investigated by wire myography. The method allows ex vivo monitoring of the transversal isometric tension developed by a vessel segment in response to different pathophysiological stimuli. Here we describe in detail how to use the wire myograph to evaluate endothelial function and vasoconstrictor or vasodilator properties of the vessel, as well as to identify and characterize different factors and molecular pathways that control vascular tone. We also describe how to use the wire myograph to analyze biomechanical and passive properties of vessels such as diameter and elasticity.en
dc.description.departmentDepto. de Biología Celular
dc.description.facultyFac. de Odontología
dc.description.refereedTRUE
dc.description.sponsorshipFondo de Investigaciones Sanitarias
dc.description.sponsorshipComunidad de Madrid/Fondo Europeo de Desarrollo Regional
dc.description.sponsorshipMinisterio de Economía, Comercio y Empresa (España)
dc.description.statuspub
dc.identifier.citationdel Campo L, Ferrer M. Wire Myography to Study Vascular Tone and Vascular Structure of Isolated Mouse Arteries. Methods Mol Biol. 2015;1339:255-76
dc.identifier.citationDel Campo L, Ferrer M (2015) Wire Myography to Study Vascular Tone and Vascular Structure of Isolated Mouse Arteries. In: Andrés V, Dorado B (eds) Methods in Mouse Atherosclerosis. Springer New York, New York, NY, pp 255–276
dc.identifier.doi10.1007/978-1-4939-2929-0_18
dc.identifier.essn1940-6029
dc.identifier.isbn978-1-4939-2928-3
dc.identifier.isbn978-1-4939-4935-9
dc.identifier.issn1064-3745
dc.identifier.officialurlhttps://doi.org/10.1007/978-1-4939-2929-0_18
dc.identifier.pmid26445795
dc.identifier.urihttps://hdl.handle.net/20.500.14352/96572
dc.language.isoeng
dc.page.final276
dc.page.initial255
dc.publication.placeNew York
dc.publisherSpringer Science+Business Media
dc.relation.ispartofseriesMethods in Molecular Biology
dc.relation.projectIDFondo de Investigaciones Sanitarias (PI1100406)
dc.relation.projectIDFondo Europeo de Desarrollo Regional and Comunidad de Madrid (S2013/ABI-2783, “INSPIRA1-CM”)
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalen
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.cdu616.12-005
dc.subject.cdu616-073.7
dc.subject.cdu579.61
dc.subject.keywordEndothelial function
dc.subject.keywordIsolated mouse arteries
dc.subject.keywordVascular reactivity
dc.subject.keywordVascular structure
dc.subject.keywordVascular tone
dc.subject.keywordWire myograph
dc.subject.ucmCiencias Biomédicas
dc.subject.ucmMicrobiología médica
dc.subject.ucmSistema cardiovascular
dc.subject.ucmDiagnóstico por imagen y medicina nuclear
dc.subject.unesco32 Ciencias Médicas
dc.subject.unesco3201.03 Microbiología Clínica
dc.subject.unesco3207.04 Patología Cardiovascular
dc.subject.unesco3314 Tecnología Médica
dc.titleWire Myography to Study Vascular Tone and Vascular Structure of Isolated Mouse Arteriesen
dc.typebook part
dc.type.hasVersionVoR
dc.volume.number1339
dspace.entity.typePublication
relation.isAuthorOfPublication34c282f4-5423-47c4-9d8b-f7832ca29c3b
relation.isAuthorOfPublication.latestForDiscovery34c282f4-5423-47c4-9d8b-f7832ca29c3b

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