Development of Geometry-Controlled All-Orthogonal BODIPY Trimers for Photodynamic Therapy and Phototheragnosis

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dc.contributor.authorPrieto Castañeda, Alejandro
dc.contributor.authorGarcía Garrido, Fernando
dc.contributor.authorDíaz Norambuena, Carolina
dc.contributor.authorEscriche Navarro, Blanca
dc.contributor.authorGarcía Fernández, Alba
dc.contributor.authorBañuelos, Jorge
dc.contributor.authorRebollar, Esther
dc.contributor.authorGarcía Moreno, Inmaculada
dc.contributor.authorMartínez Máñez, Ramón
dc.contributor.authorMoya Cerero, Santiago De La
dc.contributor.authorRodríguez Agarrabeitia, Antonia
dc.contributor.authorOrtiz García, María Josefa
dc.date.accessioned2023-06-22T11:03:47Z
dc.date.available2023-06-22T11:03:47Z
dc.date.issued2022-05-16
dc.descriptionCRUE-CSIC (Acuerdos Transformativos 2022)
dc.description.abstractWe have established an easy synthetic protocol for selectively developing all-orthogonal BODIPY trimers with unprecedented geometries on the basis of selecting methyl oxidation versus electrophilic formylation of key dimeric precursors. Photophysical characterization together with biological assays unraveled the most suitable BODIPY−BODIPY geometrical arrangements within the trimer, forcing them to serve as molecular platforms for the development of new, advanced heavy-atom-free photosensitizers for photodynamic therapy and phototheragnosis.en
dc.description.departmentDepto. de Química Orgánica
dc.description.facultyFac. de Ciencias Químicas
dc.description.refereedTRUE
dc.description.sponsorshipMinisterio de Ciencia, Innovación y Universidades (España)
dc.description.sponsorshipInstituto de Salud Carlos III
dc.description.sponsorshipGobierno Vasco
dc.description.sponsorshipGeneralitat Valenciana
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/74782
dc.identifier.citationPrieto Castañeda, A., García Garrido, F., Díaz Norambuena, C. et al. «Development of Geometry-Controlled All-Orthogonal BODIPY Trimers for Photodynamic Therapy and Phototheragnosis». Organic Letters, vol. 24, n.o 20, mayo de 2022, pp. 3636-41. DOI.org (Crossref), https://doi.org/10.1021/acs.orglett.2c01169.
dc.identifier.doi10.1021/acs.orglett.2c01169
dc.identifier.issn1523-7060
dc.identifier.officialurlhttps://doi.org/10.1021/acs.orglett.2c01169
dc.identifier.urihttps://hdl.handle.net/20.500.14352/72062
dc.issue.number20
dc.journal.titleOrganic Letters
dc.language.isoeng
dc.page.final3641
dc.page.initial3636
dc.publisherACS
dc.relation.projectID(PID2020-11455GB-C31, -C32, and -C33 and RTI2018-100910-B-C41)
dc.relation.projectID(IFI19/00026)
dc.relation.projectID(IT1639-22)
dc.relation.projectID(PROMETEO 2018/024)
dc.rightsAtribución 3.0 España
dc.rights.accessRightsopen access
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/es/
dc.subject.cdu547
dc.subject.ucmQuímica orgánica (Química)
dc.subject.unesco2306 Química Orgánica
dc.titleDevelopment of Geometry-Controlled All-Orthogonal BODIPY Trimers for Photodynamic Therapy and Phototheragnosisen
dc.typejournal article
dc.volume.number24
dspace.entity.typePublication
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relation.isAuthorOfPublication.latestForDiscoverybee889c2-938d-48d9-8748-01e3c8bf5614
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