Para depositar en Docta Complutense, identifícate con tu correo @ucm.es en el SSO institucional. Haz clic en el desplegable de INICIO DE SESIÓN situado en la parte superior derecha de la pantalla. Introduce tu correo electrónico y tu contraseña de la UCM y haz clic en el botón MI CUENTA UCM, no autenticación con contraseña.

Development of Geometry-Controlled All-Orthogonal BODIPY Trimers for Photodynamic Therapy and Phototheragnosis

Thumbnail Image

Download

Download acs.orglett.2c01169.pdf (1.84 MB)

Official URL

https://doi.org/10.1021/acs.orglett.2c01169

Full text at PDC

Publication date

2022

Authors

Advisors (or tutors)

Editors

Journal Title

Journal ISSN

Volume Title

Publisher

ACS
Citations
Google Scholar
Exportar
DC QDC MarcXML RDF MODS METS ORE-ATOM

URI

https://hdl.handle.net/20.500.14352/72062

Citation

Prieto Castañeda, A., García Garrido, F., Díaz Norambuena, C. et al. «Development of Geometry-Controlled All-Orthogonal BODIPY Trimers for Photodynamic Therapy and Phototheragnosis». Organic Letters, vol. 24, n.o 20, mayo de 2022, pp. 3636-41. DOI.org (Crossref), https://doi.org/10.1021/acs.orglett.2c01169.

Abstract

We have established an easy synthetic protocol for selectively developing all-orthogonal BODIPY trimers with unprecedented geometries on the basis of selecting methyl oxidation versus electrophilic formylation of key dimeric precursors. Photophysical characterization together with biological assays unraveled the most suitable BODIPY−BODIPY geometrical arrangements within the trimer, forcing them to serve as molecular platforms for the development of new, advanced heavy-atom-free photosensitizers for photodynamic therapy and phototheragnosis.

Research Projects

Organizational Units

Journal Issue

Description

CRUE-CSIC (Acuerdos Transformativos 2022)

UCM subjects

Química orgánica (Química)

Unesco subjects

2306 Química Orgánica

Keywords

Collections

Artículos