Omalizumab restores the ability of human plasmacytoid dendritic cells to induce Foxp3+Tregs

Thumbnail Image

Download

Omalizumab_:and_Tregs.pdf (387.6 KB)

Official URL

https://doi.org/10.1183/13993003.00751-2020

Full text at PDC

Publication date

2021

Authors

Advisors (or tutors)

Editors

Journal Title

Journal ISSN

Volume Title

Publisher

European Respiratory Society
Citations
Google Scholar
Exportar
DC QDC MarcXML RDF MODS METS ORE-ATOM

URI

https://hdl.handle.net/20.500.14352/95318

Citation

López-Abente J, Benito-Villalvilla C, Jaumont X, Pfister P, Tassinari P, Palomares O. Omalizumab restores the ability of human plasmacytoid dendritic cells to induce Foxp3+Tregs. Eur Respir J. 2021 Jan 14;57(1):2000751. doi: 10.1183/13993003.00751-2020

Abstract

IgE-FcεR1 cross-linking on human pDCs impairs their capacity to generate regulatory T-cells and in vitro omalizumab restores this ability. These findings may pave the way for novel biomarkers to assess omalizumab clinical efficacy and responder patients.

Research Projects

Organizational Units

Journal Issue

Description

UCM subjects

Bioquímica (Medicina), Bioquímica (Química), Inmunología

Unesco subjects

2403 Bioquímica, 2302 Bioquímica, 2412 Inmunología, 3207.01 Alergias

Keywords

Collections

Artículos