Omalizumab restores the ability of human plasmacytoid dendritic cells to induce Foxp3+Tregs

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dc.contributor.authorLópez Abente, Jacobo
dc.contributor.authorBenito Villalvilla, Cristina
dc.contributor.authorJaumont, Xavier
dc.contributor.authorPfister, Pascal
dc.contributor.authorTassinari, Paolo
dc.contributor.authorPalomares Gracia, Óscar
dc.date.accessioned2024-01-25T10:12:43Z
dc.date.available2024-01-25T10:12:43Z
dc.date.issued2021
dc.description.abstractIgE-FcεR1 cross-linking on human pDCs impairs their capacity to generate regulatory T-cells and in vitro omalizumab restores this ability. These findings may pave the way for novel biomarkers to assess omalizumab clinical efficacy and responder patients.
dc.description.departmentDepto. de Bioquímica y Biología Molecular
dc.description.facultyFac. de Ciencias Químicas
dc.description.refereedTRUE
dc.description.sponsorshipMinisterio de Ciencia, Innovación y Universidades (España)
dc.description.sponsorshipNovartis
dc.description.sponsorshipMinisterio de Economía y Competitividad (España)
dc.description.statuspub
dc.identifier.citationLópez-Abente J, Benito-Villalvilla C, Jaumont X, Pfister P, Tassinari P, Palomares O. Omalizumab restores the ability of human plasmacytoid dendritic cells to induce Foxp3+Tregs. Eur Respir J. 2021 Jan 14;57(1):2000751. doi: 10.1183/13993003.00751-2020
dc.identifier.doi10.1183/13993003.00751-2020
dc.identifier.issn0903-1936
dc.identifier.officialurlhttps://doi.org/10.1183/13993003.00751-2020
dc.identifier.relatedurlhttps://pubmed.ncbi.nlm.nih.gov/32675208/
dc.identifier.urihttps://hdl.handle.net/20.500.14352/95318
dc.issue.number1
dc.journal.titleEuropean Respiratory Journal
dc.language.isoeng
dc.publisherEuropean Respiratory Society
dc.relation.projectIDSAF-2017-84978-R
dc.rightsAttribution 4.0 Internationalen
dc.rights.accessRightsrestricted access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.cdu577.1
dc.subject.keywordOmalizumab
dc.subject.keywordIgE
dc.subject.keywordPlasmacytoid dendritic cells
dc.subject.keywordRegulatory T cells
dc.subject.ucmBioquímica (Medicina)
dc.subject.ucmBioquímica (Química)
dc.subject.ucmInmunología
dc.subject.unesco2403 Bioquímica
dc.subject.unesco2302 Bioquímica
dc.subject.unesco2412 Inmunología
dc.subject.unesco3207.01 Alergias
dc.titleOmalizumab restores the ability of human plasmacytoid dendritic cells to induce Foxp3+Tregs
dc.typejournal article
dc.type.hasVersionVoR
dc.volume.number57
dspace.entity.typePublication
relation.isAuthorOfPublication3356f6c6-c499-44de-8faf-0e69c97d0167
relation.isAuthorOfPublication849d1c21-090b-4cfa-8f5b-857c7276b26d
relation.isAuthorOfPublication.latestForDiscovery3356f6c6-c499-44de-8faf-0e69c97d0167

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