Aviso: para depositar documentos, por favor, inicia sesión e identifícate con tu cuenta de correo institucional de la UCM con el botón MI CUENTA UCM. No emplees la opción AUTENTICACIÓN CON CONTRASEÑA
 

Aplastic anaemia treated using eltrombopag in a dog

Loading...
Thumbnail Image

Full text at PDC

Publication date

2023

Advisors (or tutors)

Editors

Journal Title

Journal ISSN

Volume Title

Publisher

Wiley
Citations
Google Scholar

Citation

Rodriguez-Cobos A, Atencia S. Aplastic anaemia treated using eltrombopag in a dog. Vet Rec Case Rep. 2023; 11:e675. https://doi.org/10.1002/vrc2.675

Abstract

A 2-year-old, neutered, female beagle was presented to a referral hospital for investigation of pancytopenia. The patient had a history of recurrent infections and, on previous blood tests, anaemia, leukopenia and thrombocytopenia were detected. At the time of presentation, the patient had been treated for 2 weeks with omeprazole, amoxicillin-clavulanic acid, marbofloxacin and gabapentin, and for 3 months with prednisolone, in decreasing doses. A bone marrow aspirate and core biopsy were performed. Hypoplastic bone marrow was observed. Once underlying infectious diseases and exposure to toxins were ruled out, a diagnosis of aplastic anaemia was made. The patient was treated with eltrombopag, a thrombopoietin receptor agonist that stimulates primitive haematopoietic stem cells, used for the treatment of aplastic anaemia in humans. One week after starting eltrombopag treatment, all the affected cellular lines were recovered. The patient continued in remission 7 months after treatment.

Research Projects

Organizational Units

Journal Issue

Description

2023 Acuerdos transformativos CRUE

UCM subjects

Keywords

Collections