Agreement between central corneal thickness measured using pentacam, ultrasound pachymetry, specular microscopy and optic biometer lenstar LS 900 and the influence of intraocular pressure
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Publication date
2014
Authors
Borrego Sanz, Lara
Saenz Frances, Federico
Bermudez Vallecilla, M. C.
Morales Fernández, Laura
Santos Bueso, Enrique
Jañez Escalada, Luis
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Publisher
Karger
Citation
Borrego Sanz, L., Saenz Frances, F., Bermudez Vallecilla, M. C. et al. «Agreement between Central Corneal Thickness Measured Using Pentacam, Ultrasound Pachymetry, Specular Microscopy and Optic Biometer Lenstar LS 900 and the Influence of Intraocular Pressure». Ophthalmologica, vol. 231, n.o 4, marzo de 2014, pp. 226-35. Silverchair, https://doi.org/10.1159/000356724.
Abstract
Purpose: To compare central corneal thickness (CCT) values obtained by Lenstar (LE), Pentacam (PC), specular microscopy (SM) and ultrasound pachymetry (UP) in healthy corneas and study their influence on intraocular pressure (IOP) readings determined by Goldmann applanation tonometry (GAT). Methods: CCT was measured in 76 healthy subjects by LE, PC, SM and UP. We established Lin's concordance correlation coefficient (ρ-C) between different techniques. The influence of CCT on GAT was established through univariate linear regression models, IOP being the dependent variable. Results: The highest ρ-C was found between LE and SM at 0.94 (95% CI: 0.91-0.96) and between LE and UP at 0.95 (95% CI: 0.94-0.97). IOP readings showed less variability when CCT was determined using LE (7.7%, B = 0.16; 95% CI: 0.004-0.28). Conclusions: Although CCT values obtained with UP, PC, SM and LE show good correlation, these methods are not completely interchangeable. The amount of IOP variation differs when CCT is determined using LE or SM.