Minimal Residual Disease Monitoring with Next-Generation Sequencing Methodologies in Hematological Malignancies
dc.contributor.author | Sánchez, Ricardo | |
dc.contributor.author | Ayala Díaz, Rosa María | |
dc.contributor.author | Martínez López, Joaquín | |
dc.date.accessioned | 2023-06-17T12:35:33Z | |
dc.date.available | 2023-06-17T12:35:33Z | |
dc.date.issued | 2019-06-10 | |
dc.description.abstract | Ultra-deep next-generation sequencing has emerged in recent years as an important diagnostic tool for the detection and follow-up of tumor burden in most of the known hematopoietic malignancies. Meticulous and high-throughput methods for the lowest possible quantified disease are needed to address the deficiencies of more classical techniques. Precision-based approaches will allow us to correctly stratify each patient based on the minimal residual disease (MRD) after a treatment cycle. In this review, we consider the most prominent ways to approach next-generation sequencing methodologies to follow-up MRD in hematological neoplasms. | |
dc.description.faculty | Fac. de Medicina | |
dc.description.refereed | TRUE | |
dc.description.status | pub | |
dc.eprint.id | https://eprints.ucm.es/id/eprint/65882 | |
dc.identifier.doi | 10.3390/ijms20112832 | |
dc.identifier.issn | 1422-0067 | |
dc.identifier.officialurl | https://doi.org/10.3390/ijms20112832 | |
dc.identifier.relatedurl | https://www.mdpi.com/1422-0067/20/11/2832 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14352/12572 | |
dc.issue.number | 11 | |
dc.journal.title | International Journal of Molecular Sciences | |
dc.language.iso | eng | |
dc.page.initial | 2832 | |
dc.publisher | MDPI | |
dc.rights | Atribución 3.0 España | |
dc.rights.accessRights | open access | |
dc.rights.uri | https://creativecommons.org/licenses/by/3.0/es/ | |
dc.subject.keyword | minimal residual disease | |
dc.subject.keyword | next-generation sequencing | |
dc.subject.keyword | clonal evolution | |
dc.subject.keyword | hematological neoplasms | |
dc.subject.keyword | high-throughput sequencing | |
dc.subject.ucm | Oncología | |
dc.subject.unesco | 3201.01 Oncología | |
dc.title | Minimal Residual Disease Monitoring with Next-Generation Sequencing Methodologies in Hematological Malignancies | |
dc.type | journal article | |
dc.volume.number | 20 | |
dspace.entity.type | Publication | |
relation.isAuthorOfPublication | e6f24d0a-7a49-49e1-8482-fd36f9fa1627 | |
relation.isAuthorOfPublication | 5d58b324-f60e-4598-941b-4a07291634a9 | |
relation.isAuthorOfPublication.latestForDiscovery | e6f24d0a-7a49-49e1-8482-fd36f9fa1627 |
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