Self-immolative polymers as novel pH-responsive gate keepers for drug delivery
| dc.contributor.author | Gisbert Garzarán, Miguel | |
| dc.contributor.author | Lozano Borregón, Daniel | |
| dc.contributor.author | Vallet Regí, María Dulce Nombre | |
| dc.contributor.author | Manzano García, Miguel | |
| dc.date.accessioned | 2024-01-29T09:42:15Z | |
| dc.date.available | 2024-01-29T09:42:15Z | |
| dc.date.issued | 2017 | |
| dc.description.abstract | A novel pH-sensitive nanocarrier based on mesoporous silica nanoparticles with self-immolative polymers blocking the pore openings is presented. Triggered release by acid pH is demonstrated, together with their in vitro biocompatibility and effective cell internalisation, which makes this new material a promising candidate for future applications in cancer treatment. | |
| dc.description.department | Depto. de Química en Ciencias Farmacéuticas | |
| dc.description.faculty | Fac. de Farmacia | |
| dc.description.refereed | TRUE | |
| dc.description.sponsorship | European Research Council | |
| dc.description.status | pub | |
| dc.identifier.citation | Gisbert-Garzaran M, Lozano D, Vallet-Regí M, Manzano M. Self-immolative polymers as novel pH-responsive gate keepers for drug delivery. RSC Adv 2017;7:132–6. https://doi.org/10.1039/C6RA26771H. | |
| dc.identifier.doi | 10.1039/c6ra26771h | |
| dc.identifier.issn | 2046-2069 | |
| dc.identifier.officialurl | https://doi.org/10.1039/c6ra26771h | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14352/95793 | |
| dc.journal.title | RSC Advances | |
| dc.language.iso | eng | |
| dc.relation.projectID | info:eu-repo/grantAgreement/EUH2020-NMP-PILOTS2015 | |
| dc.relation.projectID | info:eu-repo/grantAgreement/ERC2015-AdGProposalno.694160 | |
| dc.rights | Attribution 4.0 International | |
| dc.rights.accessRights | open access | |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
| dc.subject.ucm | Ciencias | |
| dc.subject.unesco | 23 Química | |
| dc.title | Self-immolative polymers as novel pH-responsive gate keepers for drug delivery | |
| dc.type | journal article | |
| dc.volume.number | 7 | |
| dspace.entity.type | Publication | |
| relation.isAuthorOfPublication | 0d246121-187b-405e-91ad-48275cebf577 | |
| relation.isAuthorOfPublication | bf1fb240-43ed-4474-8dc0-2491074f4ad3 | |
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| relation.isAuthorOfPublication | 2a7febe9-6dd2-4117-aa12-552e54c12bd3 | |
| relation.isAuthorOfPublication.latestForDiscovery | 0d246121-187b-405e-91ad-48275cebf577 |
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