A comparison study of cognitive deficits in radiologically and clinically isolated syndromes
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2016
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Labiano-Fontcuberta, A., Martínez-Ginés, M. L., Aladro, Y., Ayuso, L., Mitchell, A. J., Puertas-Martín, V., Cerezo, M., Higueras, Y., & Benito-León, J. (2016). A comparison study of cognitive deficits in radiologically and clinically isolated syndromes. Multiple Sclerosis, 22(2), 250-253. https://doi.org/10.1177/1352458515591072
Abstract
Up until now, no information has existed regarding a comparison of the pattern and frequency of cognitive deficits between radiologically isolated syndrome (RIS) and clinically isolated syndrome (CIS) patients. Within this objective, Rao's Brief Repeatable Battery and Stroop test were administered to 28 RIS patients, 25 CIS patients, and 22 healthy controls. Conclusions: The prevalence of cognitive deficits in RIS was similar to that of CIS. Cognitive deficits seem to be present in RIS patients regardless of the presence of risk factors for a future symptomatic demyelinating event.
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Dr Benito-Leon is supported by the National Institutes of Health, Bethesda, MD, USA (NINDS #R01 NS39422), the Commission of the European Union (grant ICT-2011-287739, NeuroTREMOR), and the Spanish Health Research Agency (grant FIS PI12/01602).
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