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Macular Thickness as a Potential Biomarker of Mild Alzheimer's Disease

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dc.contributor.authorGarcía Martín, Elena Salobrar
dc.contributor.authorRojas López, María Blanca
dc.contributor.authorRamírez Sebastián, Ana Isabel
dc.contributor.authorHoz Montañana, María Rosa De
dc.contributor.authorSalazar Corral, Juan José
dc.contributor.authorYubero Pancorbo, Raquel
dc.contributor.authorGil Gregorio, Pedro
dc.contributor.authorTriviño Casado, Alberto
dc.contributor.authorRamírez Sebastián, José Manuel
dc.date.accessioned2023-06-19T15:05:17Z
dc.date.available2023-06-19T15:05:17Z
dc.date.issued2014-03-18
dc.description.abstractAlthough several postmortem findings in the retina of patients with Alzheimer's disease (AD) are available, new biomarkers for early diagnosis and follow-up of AD are still lacking. It has been postulated that the defects in the retinal nerve fiber layer (RNFL) may be the earliest sign of AD, even before damage to the hippocampal region that affects memory. This fact may reflect retinal neuronal-ganglion cell death and axonal loss in the optic nerve in addition to aging.en
dc.description.departmentUnidad Docente de Inmunología, Oftalmología y ORL
dc.description.facultyFac. de Óptica y Optometría
dc.description.refereedTRUE
dc.description.sponsorshipMinisterio de Ciencia, Innovación y Universidades (España)
dc.description.sponsorshipRedes Temáticas de Investigación Cooperativa
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/39714
dc.identifier.citationGarcía Martín, E. S., Rojas López, M. B., ramírez Sebastián, A. I. et al. «Macular Thickness as a Potential Biomarker of Mild Alzheimer’s Disease». Ophthalmology, vol. 121, n.o 5, mayo de 2014, pp. 1149-1151.e3. DOI.org (Crossref), https://doi.org/10.1016/j.ophtha.2013.12.023.
dc.identifier.doi10.1016/j.ophtha.2013.12.023
dc.identifier.issn0161-6420
dc.identifier.officialurlhttp://dx.doi.org/10.1016/j.ophtha.2013.12.023
dc.identifier.relatedurlhttp://www.aaojournal.org/article/S0161-6420(13)01229-3/abstract
dc.identifier.urihttps://hdl.handle.net/20.500.14352/35304
dc.issue.number5
dc.journal.titleOphthalmology
dc.language.isoeng
dc.page.final1151
dc.page.initial1149
dc.publisherElsevier / American Academy of Ophthalmology
dc.relation.projectIDISCIII RD12/ 0034/0002
dc.rightsAtribución-NoComercial 3.0 España
dc.rights.accessRightsopen access
dc.rights.urihttps://creativecommons.org/licenses/by-nc/3.0/es/
dc.subject.cdu616.894-053.9
dc.subject.cdu617.736
dc.subject.keywordMacular thickness
dc.subject.keywordBiomarkers
dc.subject.keywordAlzheimer's disease
dc.subject.ucmNeurociencias (Medicina)
dc.subject.ucmOftalmología
dc.subject.ucmAnatomía ocular
dc.subject.unesco2490 Neurociencias
dc.subject.unesco3201.09 Oftalmología
dc.titleMacular Thickness as a Potential Biomarker of Mild Alzheimer's Diseaseen
dc.typejournal article
dc.volume.number121
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