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Macular Thickness as a Potential Biomarker of Mild Alzheimer's Disease

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http://dx.doi.org/10.1016/j.ophtha.2013.12.023

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2014

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Elsevier / American Academy of Ophthalmology
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https://hdl.handle.net/20.500.14352/35304

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García Martín, E. S., Rojas López, M. B., ramírez Sebastián, A. I. et al. «Macular Thickness as a Potential Biomarker of Mild Alzheimer’s Disease». Ophthalmology, vol. 121, n.o 5, mayo de 2014, pp. 1149-1151.e3. DOI.org (Crossref), https://doi.org/10.1016/j.ophtha.2013.12.023.

Abstract

Although several postmortem findings in the retina of patients with Alzheimer's disease (AD) are available, new biomarkers for early diagnosis and follow-up of AD are still lacking. It has been postulated that the defects in the retinal nerve fiber layer (RNFL) may be the earliest sign of AD, even before damage to the hippocampal region that affects memory. This fact may reflect retinal neuronal-ganglion cell death and axonal loss in the optic nerve in addition to aging.

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Neurociencias (Medicina), Oftalmología, Anatomía ocular

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2490 Neurociencias, 3201.09 Oftalmología

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