Microfluidic fabrication of vesicles with hybrid lipid/nanoparticle bilayer membranes

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dc.contributor.authorPerrotton, Julie
dc.contributor.authorAhijado Guzmán, Rubén
dc.contributor.authorMoleiro, Lara
dc.contributor.authorTinao, Berta
dc.contributor.authorGuerrero Martínez, Andrés
dc.contributor.authorAmstad, Esther
dc.contributor.authorMonroy Muñoz, Francisco
dc.contributor.authorArriaga, Laura
dc.date.accessioned2024-01-16T08:42:10Z
dc.date.available2024-01-16T08:42:10Z
dc.date.issued2019
dc.description.abstractHybrid lipid/nanoparticle membranes are suitable model systems both to study the complex interactions between nanoparticles and biological membranes, and to demonstrate technological concepts in cellular sensing and drug delivery. Unfortunately, embedding nanoparticles into the bilayer membrane of lipid vesicles is challenging due to the poor control over the vesicle fabrication process of conventional methodologies and the fragility of the modified lipid bilayer assembly. Here, the utility of water-in-oil-in-water double emulsion drops with ultrathin oil shells as templates to form vesicles with hybrid lipid/nanoparticle membranes is reported.
dc.description.departmentDepto. de Química Física
dc.description.facultyFac. de Ciencias Químicas
dc.description.refereedTRUE
dc.description.sponsorshipEuropean Commission
dc.description.sponsorshipMinisterio de Economía y Competitividad (España)
dc.description.sponsorshipComunidad de Madrid
dc.description.statuspub
dc.identifier.citationPerrotton, Julie, et al. «Microfluidic Fabrication of Vesicles with Hybrid Lipid/Nanoparticle Bilayer Membranes». Soft Matter, vol. 15, n.o 6, 2019, pp. 1388-95. https://doi.org/10.1039/C8SM02050G.
dc.identifier.doi10.1039/c8sm02050g
dc.identifier.issn1744-683X
dc.identifier.officialurlhttps://doi.org/10.1039/c8sm02050g
dc.identifier.urihttps://hdl.handle.net/20.500.14352/93252
dc.issue.number6
dc.journal.titleSoft Matter
dc.language.isoeng
dc.page.final1395
dc.page.initial1388
dc.publisherRoyal Society of Chemistry
dc.relation.projectID(GUVs-3G, PIOF-2012- 332078)
dc.relation.projectID(IJCI-2014-22461)
dc.relation.projectID(FIS2015-70339- C2-1-R)
dc.relation.projectID(S2013/MIT-2807)
dc.rights.accessRightsmetadata only access
dc.subject.cdu544
dc.subject.keywordBiological membranes
dc.subject.keywordControlled drug delivery
dc.subject.keywordCytology
dc.subject.keywordDrops
dc.subject.keywordEmulsification
dc.subject.keywordFabrication
dc.subject.keywordLipid bilayers
dc.subject.keywordMicrofluidics
dc.subject.keywordPhase separation
dc.subject.keywordTargeted drug delivery
dc.subject.ucmCiencias
dc.subject.unesco23 Química
dc.titleMicrofluidic fabrication of vesicles with hybrid lipid/nanoparticle bilayer membranes
dc.typejournal article
dc.volume.number15
dspace.entity.typePublication
relation.isAuthorOfPublication4af13c82-c400-4bf3-9103-829be26b4d63
relation.isAuthorOfPublication22761001-a3ad-4b9e-b47f-bfd3ba5f8a57
relation.isAuthorOfPublicationbe319c4d-3f68-44c3-bbfc-a0bb85e27477
relation.isAuthorOfPublication.latestForDiscovery4af13c82-c400-4bf3-9103-829be26b4d63
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