Highly Tigecycline-Resistant Klebsiella pneumoniae Sequence Type 11 (ST11) and ST147 Isolates from Companion Animals

Martinez Ovejero, Cristina; Thomas-Lopez, Daniel; Hoefer, Andreas; Moyano, Gabriel; Escudero García-Calderón, José Antonio; González Zorn, Bruno; Martín Espada, María Del Carmen; Montero Serra, Natalia

Highly Tigecycline-Resistant Klebsiella pneumoniae Sequence Type 11 (ST11) and ST147 Isolates from Companion Animals

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Official URL

https://journals.asm.org/doi/10.1128/aac.02640-16?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed

Publication date

2017

Authors

Martinez Ovejero, Cristina

Thomas-Lopez, Daniel

Hoefer, Andreas

Moyano, Gabriel

Escudero García-Calderón, José Antonio

González Zorn, Bruno

Martín Espada, María Del Carmen

Montero Serra, Natalia

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URI

https://hdl.handle.net/20.500.14352/94363

Abstract

In this study, we characterized two tigecycline-resistant Klebsiella pneumoniae isolates from dog urine samples. The isolates were genetically unrelated, belonging to sequence type 11 (ST11) and ST147, both classically related to human isolates. To the best of our knowledge, this is the first identification of tigecycline-resistant isolates from animals. We unveil here the worrisome circulation among animals of bacterial clones resistant to this last-resort antibiotic.

Description

C.M.O. and J.A.E. designed the study, performed the experiments, analyzed and interpreted the results, and wrote the draft manuscript. C.M.-E. collected the samples, provided the isolates for this study, and revised and approved the final version of the manuscript. N.M. performed the experiments, D.T.L. and G.M. analyzed and interpreted the results, and A.H. revised the manuscript. B.G.Z. conceived, designed, and coordinated the study and revised and approved the final versión of the manuscript.