Highly Tigecycline-Resistant Klebsiella pneumoniae Sequence Type 11 (ST11) and ST147 Isolates from Companion Animals

dc.contributor.authorMartinez Ovejero, Cristina
dc.contributor.authorThomas-Lopez, Daniel
dc.contributor.authorHoefer, Andreas
dc.contributor.authorMoyano, Gabriel
dc.contributor.authorEscudero García-Calderón, José Antonio
dc.contributor.authorGonzález Zorn, Bruno
dc.contributor.authorMartín Espada, María Del Carmen
dc.contributor.authorMontero Serra, Natalia
dc.date.accessioned2024-01-22T12:16:03Z
dc.date.available2024-01-22T12:16:03Z
dc.date.issued2017-05-24
dc.descriptionC.M.O. and J.A.E. designed the study, performed the experiments, analyzed and interpreted the results, and wrote the draft manuscript. C.M.-E. collected the samples, provided the isolates for this study, and revised and approved the final version of the manuscript. N.M. performed the experiments, D.T.L. and G.M. analyzed and interpreted the results, and A.H. revised the manuscript. B.G.Z. conceived, designed, and coordinated the study and revised and approved the final versión of the manuscript.
dc.description.abstractIn this study, we characterized two tigecycline-resistant Klebsiella pneumoniae isolates from dog urine samples. The isolates were genetically unrelated, belonging to sequence type 11 (ST11) and ST147, both classically related to human isolates. To the best of our knowledge, this is the first identification of tigecycline-resistant isolates from animals. We unveil here the worrisome circulation among animals of bacterial clones resistant to this last-resort antibiotic.
dc.description.departmentDepto. de Sanidad Animal
dc.description.facultyFac. de Veterinaria
dc.description.refereedTRUE
dc.description.sponsorshipUnión Europea (EvoTAR282004-FP7; EFFORT613754FP7)
dc.description.sponsorshipComunidad de Madrid (2016-T1/BIO-1105)
dc.description.statuspub
dc.identifier.doi10.1128/aac.02640-16
dc.identifier.issn0066-4804
dc.identifier.issn1098-6596
dc.identifier.officialurlhttps://journals.asm.org/doi/10.1128/aac.02640-16?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed
dc.identifier.relatedurlhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444156/
dc.identifier.urihttps://hdl.handle.net/20.500.14352/94363
dc.issue.number6
dc.journal.titleAntimicrobial Agents and Chemotherapy
dc.language.isoeng
dc.page.initiale02640-16
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalen
dc.rights.accessRightsrestricted access
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.cdu636.09
dc.subject.keywordKlebsiella
dc.subject.keywordDrugefflux
dc.subject.keywordEffluxpumps
dc.subject.keywordPets
dc.subject.keywordPlasmids
dc.subject.keywordTigecycline
dc.subject.ucmVeterinaria
dc.subject.unesco3109 Ciencias Veterinarias
dc.titleHighly Tigecycline-Resistant Klebsiella pneumoniae Sequence Type 11 (ST11) and ST147 Isolates from Companion Animals
dc.typejournal article
dc.type.hasVersionVoR
dc.volume.number61
dspace.entity.typePublication
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relation.isAuthorOfPublicationabbfe61a-3e58-4cfb-85fc-d2e2ec46b0a3
relation.isAuthorOfPublication35bd56d1-9057-441d-a437-50ee7bf6f0b5
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relation.isAuthorOfPublication.latestForDiscoveryf2840ea1-2146-4244-babd-79c986a18986
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