Diferencias sexuales en la expresión genética del fenotipo obeso en población infanto-juvenil de Argentina y España
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2025
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Universidad Complutense de Madrid
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Abstract
En la presente investigación se analiza la asociación entre 34 polimorfismos de un solo nucleótido (SNPs) de manera aislada y su combinación como puntuaciones de riesgo poligénico, con variables antropométricas informativas de la adiposidad en población infanto-juvenil argentina y española. El objetivo fundamental ha sido evaluar las posibles diferencias sexuales y poblacionales en la asociación genotipo-fenotipo antropométrico para la obesidad común en una fase temprana de la ontogenia...
The present investigation analyzes the association between 34 single nucleotide polymorphisms (SNPs) in isolation and their combination as polygenic risk scores, with anthropometric variables informative of adiposity in Argentinean and Spanish infant-juvenile population. The main objective has been to evaluate possible sex and population differences in the genotype-anthropometric phenotype association for common obesity at an early stage of ontogeny...
The present investigation analyzes the association between 34 single nucleotide polymorphisms (SNPs) in isolation and their combination as polygenic risk scores, with anthropometric variables informative of adiposity in Argentinean and Spanish infant-juvenile population. The main objective has been to evaluate possible sex and population differences in the genotype-anthropometric phenotype association for common obesity at an early stage of ontogeny...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Ciencias Biológicas, leída el 23-01-2025