Oncosuppressive functions of tribbles pseudokinase 3

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https://doi.org/10.1042/BST20150124

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2015

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Portland Press
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https://hdl.handle.net/20.500.14352/125713

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Salazar M, Lorente M, Orea-Soufi A, Dávila D, Erazo T, Lizcano J, Carracedo A, Kiss-Toth E, Velasco G. Oncosuppressive functions of tribbles pseudokinase 3. Biochemical Society Transactions 2015;43:1122–6. https://doi.org/10.1042/BST20150124.

Abstract

Tribbles pseudokinase 3 (TRIB3) belongs to the tribbles family of pseudokinases. In this article, we summarize several observation obtained by our laboratories supporting that TRIB3 plays a crucial role in the anti-cancer activity of cannabinoids (a novel family of potential anti-cancer agents derived from marijuana) and that TRIB3 genetic inactivation enhances cancer generation and progression.

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Biología molecular (Biología), Bioquímica (Biología), Oncología, Farmacología (Medicina)

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2403 Bioquímica, 2407 Biología Celular, 3201.01 Oncología, 3209 Farmacología

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