Oncosuppressive functions of tribbles pseudokinase 3

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dc.contributor.authorSalazar Roa, María
dc.contributor.authorLorente Pérez, María Del Mar
dc.contributor.authorOrea Soufi, Alba
dc.contributor.authorDavila, David
dc.contributor.authorErazo, Tatiana
dc.contributor.authorLizcano, Jose
dc.contributor.authorCarracedo, Arkaitz
dc.contributor.authorKiss-Toth, Endre
dc.contributor.authorVelasco Díez, Guillermo
dc.date.accessioned2025-11-04T17:15:06Z
dc.date.available2025-11-04T17:15:06Z
dc.date.issued2015-10
dc.description.abstractTribbles pseudokinase 3 (TRIB3) belongs to the tribbles family of pseudokinases. In this article, we summarize several observation obtained by our laboratories supporting that TRIB3 plays a crucial role in the anti-cancer activity of cannabinoids (a novel family of potential anti-cancer agents derived from marijuana) and that TRIB3 genetic inactivation enhances cancer generation and progression.
dc.description.departmentDepto. de Bioquímica y Biología Molecular
dc.description.facultyFac. de Ciencias Biológicas
dc.description.refereedTRUE
dc.description.sponsorshipEuropean Commission
dc.description.sponsorshipMinisterio de Economía y Competitividad (España)
dc.description.sponsorshipEusko Jaurlaritza
dc.description.sponsorshipInstituto de Salud Carlos III (España)
dc.description.sponsorshipFundación Mutua Madrileña
dc.description.sponsorshipFundació La Marató de TV3
dc.description.sponsorshipBreast Cancer Campaign
dc.description.statuspub
dc.identifier.citationSalazar M, Lorente M, Orea-Soufi A, Dávila D, Erazo T, Lizcano J, Carracedo A, Kiss-Toth E, Velasco G. Oncosuppressive functions of tribbles pseudokinase 3. Biochemical Society Transactions 2015;43:1122–6. https://doi.org/10.1042/BST20150124.
dc.identifier.doi10.1042/BST20150124
dc.identifier.essn1470-8752
dc.identifier.issn0300-5127
dc.identifier.officialurlhttps://doi.org/10.1042/BST20150124
dc.identifier.relatedurlhttps://www.sciencedirect.com/org/science/article/abs/pii/S1470875215001191
dc.identifier.urihttps://hdl.handle.net/20.500.14352/125713
dc.issue.number5
dc.journal.titleBiochemical Society Transactions
dc.language.isoeng
dc.page.final1126
dc.page.initial1122
dc.publisherPortland Press
dc.relation.projectIDinfo:eu-repo/grantAgreement/MICINN//PS09%2F01401/ES/MECANISMOS DE REGULACION DE LA AUTOFAGIA EN CELULAS TUMORALES/
dc.relation.projectIDinfo:eu-repo/grantAgreement/MINECO//PI12%2F02248/ES/Mecanismos de regulación de la autofagia en células tumorales: muerte mediada por autofagia en respuesta a fármacos antitumorales y participación en el control de la tumorigénesis/
dc.relation.projectIDinfo:eu-repo/grantAgreement/MICINN//IT2009-0053/ES/IT2009-0053/
dc.rights.accessRightsrestricted access
dc.subject.cdu577.2
dc.subject.cdu615.015
dc.subject.cdu616-006
dc.subject.keywordAnimal models of cancer
dc.subject.keywordAutophagy
dc.subject.keywordCannabinoids
dc.subject.keywordEndoplasmic reticulum (ER) stress
dc.subject.keywordTribbles pseudokinases
dc.subject.ucmBiología molecular (Biología)
dc.subject.ucmBioquímica (Biología)
dc.subject.ucmOncología
dc.subject.ucmFarmacología (Medicina)
dc.subject.unesco2403 Bioquímica
dc.subject.unesco2407 Biología Celular
dc.subject.unesco3201.01 Oncología
dc.subject.unesco3209 Farmacología
dc.titleOncosuppressive functions of tribbles pseudokinase 3
dc.typejournal article
dc.type.hasVersionVoR
dc.volume.number43
dspace.entity.typePublication
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relation.isAuthorOfPublication974345b1-6b30-49ae-9724-2e4714f80000
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relation.isAuthorOfPublication4a33b5e2-6540-4927-ab0d-bc37f5cd8b5b
relation.isAuthorOfPublication.latestForDiscovery85418c2e-51eb-43c9-a82f-05a96903381f

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