Evaluation of a Novel Αb Εxterno MicroShunt for the Treatment of Glaucoma

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dc.contributor.authorBurgos Blasco, Bárbara
dc.contributor.authorGarcía Feijoo, Julián
dc.contributor.authorPerucho González, Lucía
dc.contributor.authorGüemes Villahoz, Noemi
dc.contributor.authorMorales Fernández, Laura
dc.contributor.authorMéndez Hernández, Carmen Dora
dc.contributor.authorMartínez De La Casa Fernández-Borrella, José María
dc.contributor.authorKonstas, Anastasios Georgios
dc.date.accessioned2023-06-22T12:55:24Z
dc.date.available2023-06-22T12:55:24Z
dc.date.issued2022-07-07
dc.description.abstractThe surgical management of glaucoma has been revolutionized by the introduction of minimally invasive glaucoma surgery (MIGS). The various MIGS options aim to meaningfully lower intraocular pressure with a better safety profile than traditional glaucoma surgery. The key clinical attributes and the emerging potential of an ab externo MicroShunt (PreserFlo™) are reviewed in the context of published evidence and clinical experience. This novel MicroShunt consists of an 8.5-mm-long tube that is implanted in the eye via an ab externo approach enabling aqueous humor drainage into the sub-Tenon's space through the formation of a bleb, similar in appearance to that created by trabeculectomy. The efficacy and safety of this procedure, the concomitant use of antimetabolites, the impact of tube positioning, and its future value in clinical practice are critically reviewed. Recent evidence has demonstrated the MicroShunt to be less effective than traditional filtration surgery, but with a significant improvement in safety. Cumulative data suggest that the new implant provides tangible clinical benefits to selected patients with glaucoma in need of further intraocular pressure (IOP) lowering. Future research should delineate the precise role of this and other MIGS options in the rapidly evolving glaucoma treatment algorithm.en
dc.description.departmentUnidad Docente de Inmunología, Oftalmología y ORL
dc.description.departmentDepto. de Inmunología, Oftalmología y ORL
dc.description.facultyFac. de Óptica y Optometría
dc.description.facultyFac. de Medicina
dc.description.refereedTRUE
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/77781
dc.identifier.citationBurgos Blasco, B., García Feijoo, J., Perucho González, L. et al. «Evaluation of a Novel Αb Εxterno MicroShunt for the Treatment of Glaucoma». Advances in Therapy, vol. 39, n.o 9, septiembre de 2022, pp. 3916-32. DOI.org (Crossref), https://doi.org/10.1007/s12325-022-02230-1.
dc.identifier.doi10.1007/s12325-022-02230-1
dc.identifier.issn0741-238X
dc.identifier.officialurlhttps://doi.org/10.1007/s12325-022-02230-1
dc.identifier.relatedurlhttps://link.springer.com/article/10.1007/s12325-022-02230-1
dc.identifier.urihttps://hdl.handle.net/20.500.14352/73330
dc.issue.number9
dc.journal.titleAdvances in Therapy
dc.language.isoeng
dc.page.final3932
dc.page.initial3916
dc.publisherSpringer Healthcare
dc.rightsAtribución-NoComercial 3.0 España
dc.rights.accessRightsopen access
dc.rights.urihttps://creativecommons.org/licenses/by-nc/3.0/es/
dc.subject.cdu617.7‑007.681
dc.subject.cdu617.7-089
dc.subject.keywordFiltration surgery
dc.subject.keywordGlaucoma
dc.subject.keywordMIGS
dc.subject.keywordMedical therapy
dc.subject.keywordPreserFlo MicroShunt.
dc.subject.ucmCirugía
dc.subject.ucmOftalmología
dc.subject.unesco3213 Cirugía
dc.subject.unesco3201.09 Oftalmología
dc.titleEvaluation of a Novel Αb Εxterno MicroShunt for the Treatment of Glaucomaen
dc.typejournal article
dc.volume.number39
dspace.entity.typePublication
relation.isAuthorOfPublication558b8023-6d72-4dff-9f99-2e60f6f31843
relation.isAuthorOfPublication533dd90f-2b34-4a5f-9cf8-ab8d19454edd
relation.isAuthorOfPublication273a99c3-2c9f-4dd0-8939-b7ff3593124c
relation.isAuthorOfPublication.latestForDiscovery558b8023-6d72-4dff-9f99-2e60f6f31843
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