Evaluation of a Novel Αb Εxterno MicroShunt for the Treatment of Glaucoma
Loading...
Official URL
Full text at PDC
Publication date
2022
Authors
Burgos Blasco, Bárbara
Perucho González, Lucía
Güemes Villahoz, Noemi
Morales Fernández, Laura
Konstas, Anastasios Georgios
Advisors (or tutors)
Editors
Journal Title
Journal ISSN
Volume Title
Publisher
Springer Healthcare
Citation
Burgos Blasco, B., García Feijoo, J., Perucho González, L. et al. «Evaluation of a Novel Αb Εxterno MicroShunt for the Treatment of Glaucoma». Advances in Therapy, vol. 39, n.o 9, septiembre de 2022, pp. 3916-32. DOI.org (Crossref), https://doi.org/10.1007/s12325-022-02230-1.
Abstract
The surgical management of glaucoma has been revolutionized by the introduction of minimally invasive glaucoma surgery (MIGS). The various MIGS options aim to meaningfully lower intraocular pressure with a better safety profile than traditional glaucoma surgery. The key clinical attributes and the emerging potential of an ab externo MicroShunt (PreserFlo™) are reviewed in the context of published evidence and clinical experience. This novel MicroShunt consists of an 8.5-mm-long tube that is implanted in the eye via an ab externo approach enabling aqueous humor drainage into the sub-Tenon's space through the formation of a bleb, similar in appearance to that created by trabeculectomy. The efficacy and safety of this procedure, the concomitant use of antimetabolites, the impact of tube positioning, and its future value in clinical practice are critically reviewed. Recent evidence has demonstrated the MicroShunt to be less effective than traditional filtration surgery, but with a significant improvement in safety. Cumulative data suggest that the new implant provides tangible clinical benefits to selected patients with glaucoma in need of further intraocular pressure (IOP) lowering. Future research should delineate the precise role of this and other MIGS options in the rapidly evolving glaucoma treatment algorithm.