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Zwitterionic ceramics for biomedical applications

dc.contributor.authorIzquierdo Barba, Isabel
dc.contributor.authorColilla Nieto, Montserrat
dc.contributor.authorVallet Regí, María Dulce Nombre
dc.date.accessioned2023-06-17T21:49:12Z
dc.date.available2023-06-17T21:49:12Z
dc.date.issued2016-08
dc.descriptionRESEARCHER ID M-3378-2014 (María Vallet Regí) ORCID 0000-0002-6104-4889 (María Vallet Regí)
dc.description.abstractBioceramics for bone tissue regeneration, local drug delivery and nanomedicine, are receiving growing attention by the biomaterials scientific community. The design of bioceramics with improved surface properties able to overcome clinical issues is a great scientific challenge. Zwitterionization of surfaces has arisen as a powerful alternative in the design of biocompatible bioceramics capable to inhibit bacterial and non-specific protein adsorption, which opens up new insights into the biomedical applications of these materials. This manuscript reviews the different approaches reported up to date for the synthesis and characterization of zwitterionic bioceramics with potential clinical applications. Statement of Significance Zwitterionic bioceramics are receiving growing attention by the biomaterials scientific community due to their great potential in bone tissue regeneration, local drug delivery and nanomedicines. Herein, the different strategies developed so far to synthesize and characterize zwitterionic bioceramics with potential clinical applications are summarized. (C) 2016 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
dc.description.departmentDepto. de Química en Ciencias Farmacéuticas
dc.description.facultyFac. de Farmacia
dc.description.refereedTRUE
dc.description.sponsorshipMinisterio de Economía y Competitividad (MINECO)
dc.description.sponsorshipAgening Network of Excellence
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/40819
dc.identifier.doi10.1016/j.actbio.2016.02.027
dc.identifier.issn1742-7061
dc.identifier.officialurlhttp://dx.doi.org/10.1016/j.actbio.2016.02.027
dc.identifier.urihttps://hdl.handle.net/20.500.14352/17588
dc.journal.titleActa Biomaterialia
dc.language.isoeng
dc.page.final211
dc.page.initial201
dc.publisherElsevier
dc.relation.projectIDMAT2012-35556
dc.relation.projectIDCSO2010-11384-E
dc.rights.accessRightsopen access
dc.subject.cdu66
dc.subject.cdu546
dc.subject.cdu615.46
dc.subject.keywordZwitterionic bioceramics
dc.subject.keywordfunctionalization
dc.subject.keywordcharacterization
dc.subject.keywordLocal drug delivery
dc.subject.keywordBone tissue regeneration
dc.subject.keywordNanomedicine
dc.subject.ucmQuímica
dc.subject.ucmIngeniería química
dc.subject.ucmMateriales
dc.subject.ucmQuímica inorgánica (Química)
dc.subject.unesco23 Química
dc.subject.unesco3303 Ingeniería y Tecnología Químicas
dc.subject.unesco3312 Tecnología de Materiales
dc.subject.unesco2303 Química Inorgánica
dc.titleZwitterionic ceramics for biomedical applications
dc.typejournal article
dc.volume.number40
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