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Optical power profiles and aberrations of a non-diffractive wavefront-shaping extended depth of focus intraocular lens

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2024-04-10
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Albarrán Diego, César
Fernández Núñez, Sara
Villanueva Gómez-Chacón, Sara
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Springer
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Purpose: This study is to evaluate the optical characteristics of a non-diffractive wavefront-shaping intraocular lens which incorporates surface refractive modifications for shaping the wavefront in order to achieve extended depth of focus (EDoF) and to assess whether the nominal power of this IOL influences the attainable add power. Methods: A commercially available optical bench NIMO TR1504 device (LAMBDA-X, Nivelles, Belgium) was employed to obtain full optical characterization of three non-diffractive EDoF intraocular lenses with + 10 D, + 20 D, and + 30 D powers. After NIMO measurements, data were computed using a custom-made MATLAB program (Mathworks, Inc., Natick, MA, USA) to evaluate the optical quality functions, such as the point spread function (PSF), wavefront profiles, and modulation transfer function (MTF) for two pupil sizes: 3 mm and 4.0 mm. Results: The non-diffractive EDoF intraocular lens showed a central serrated power profile behavior with additions of + 2.00 to + 2.50 D over the nominal power. Higher order aberrations were found to be driven mainly by the spherical aberration, with almost null comatic influence. Optical quality metrics showed good values, better for a 3 mm pupil compared to a 4.5 mm one, as expected. The three IOL powers tested showed a very similar behavior in terms of power and aberrometric profiles, with minimal to null differences related to the nominal power. Conclusion: The non-diffractive wavefront-shaping EDoF intraocular lens achieves a near addition up to + 2.50 D aiming for an extended range of vision, almost independently of the base power.
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2023 Acuerdos transformativos CRUE-CSIC Received: 29 December 2023 / Revised: 28 February 2024 / Accepted: 27 March 2024
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Garzón N, Gómez-Pedrero JA, Albarrán-Diego C, Fernández-Núñez S, Villanueva Gómez-Chacón S, García-Montero M. Optical power profiles and aberrations of a non-diffractive wavefront-shaping extended depth of focus intraocular lens. Graefes Arch Clin Exp Ophthalmol. 2024 Apr 10. doi: 10.1007/s00417-024-06469-y. Epub ahead of print. PMID: 38597962.
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