Ocular Exploration in the Diagnosis and Follow-Up of the Alzheimer’s Dementia

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dc.book.titleAlzheimer’s Disease
dc.contributor.authorGarcía Martín, Elena Salobrar
dc.contributor.authorHoz Montañana, María Rosa de
dc.contributor.authorRamírez Sebastián, Ana Isabel
dc.contributor.authorSalazar Corral, Juan José
dc.contributor.authorRojas Lozano, Pilar
dc.contributor.authorLópez Cuenca, Inés
dc.contributor.authorFernández Albarral, José Antonio
dc.contributor.authorRamirez Sebastian, Jose Manuel
dc.date.accessioned2023-06-17T10:10:55Z
dc.date.available2023-06-17T10:10:55Z
dc.date.issued2019-12-20
dc.descriptionPublished: November 21, 2019
dc.description.abstractThe retina is part of the central nervous system (CNS), and therefore, in Alzheimer’s disease (AD), retinal and optic nerve degeneration could take place. This degeneration leads to neurofunctional changes that can be detected early and followed up throughout the evolution of the disease. As opposed to other CNS structures, the eye is easily accessible for in vivo observation. Retinal organization allows for the identification of its different neurons, and in consequence, detection of minimal changes taking place during neurodegeneration is possible. Functional vision studies performed on AD patients in recent years have shown how visual acuity, contrast sensitivity, color vision, and visual integration vary with the progression of neurodegeneration. The development of optical coherence tomography in ophthalmology has meant a breakthrough in retinal exploratory techniques, allowing the obtention of high-resolution images using light. This technique enables retinal analysis in the earliest stages of AD, being considered as a biomarker of neuronal damage. Given AD’s high prevalence and its expected increase, it is important to perform easy tests that cause minimal discomfort to the patients at a low cost while offering abundant information on the stage of the disease.
dc.description.departmentUnidad Docente de Inmunología, Oftalmología y ORL
dc.description.facultyFac. de Óptica y Optometría
dc.description.refereedTRUE
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/58895
dc.identifier.doi10.15586/alzheimersdisease.2019.ch10
dc.identifier.isbn978-0-646-80968-7
dc.identifier.officialurlhttp://dx.doi.org/10.15586/alzheimersdisease.2019.ch10
dc.identifier.relatedurlhttps://codonpublications.com/index.php/codon/catalog/book/115
dc.identifier.urihttps://hdl.handle.net/20.500.14352/8703
dc.language.isoeng
dc.page.final177
dc.page.initial159
dc.publication.placeBrisbane
dc.publisherCodon Publications
dc.rightsAtribución-NoComercial 3.0 España
dc.rights.accessRightsopen access
dc.rights.urihttps://creativecommons.org/licenses/by-nc/3.0/es/
dc.subject.cdu616.894-053.9
dc.subject.cdu617.735-073
dc.subject.cdu616.8-003.8
dc.subject.keywordAlzheimer’s disease
dc.subject.keywordBiomarker
dc.subject.keywordNeurodegeneration
dc.subject.keywordRetina
dc.subject.keywordVisual system
dc.subject.ucmNeurociencias (Medicina)
dc.subject.ucmOftalmología
dc.subject.ucmOptometría
dc.subject.ucmTécnicas de la imagen
dc.subject.unesco2490 Neurociencias
dc.subject.unesco3201.09 Oftalmología
dc.subject.unesco2209.15 Optometría
dc.titleOcular Exploration in the Diagnosis and Follow-Up of the Alzheimer’s Dementia
dc.typebook part
dc.volume.numberCap.10
dspace.entity.typePublication
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relation.isAuthorOfPublication.latestForDiscovery554437df-fa3d-41e1-862c-bcdda1dbd67a
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