Spoligotyping Profile Change Caused by Deletion of a Direct Variable Repeat in a Mycobacterium tuberculosis Isogenic Laboratory Strain
dc.contributor.author | Aranaz Martín, Alicia | |
dc.contributor.author | Romero Martínez, Beatriz | |
dc.contributor.author | Montero Serra, Natalia | |
dc.contributor.author | Álvarez Sánchez, Julio | |
dc.contributor.author | Bezos Garrido, Javier | |
dc.contributor.author | Juan Ferré, Lucía De | |
dc.contributor.author | Mateos García, Ana Isabel | |
dc.contributor.author | Domínguez Rodríguez, Lucas José | |
dc.date.accessioned | 2024-01-17T08:06:08Z | |
dc.date.available | 2024-01-17T08:06:08Z | |
dc.date.issued | 2004 | |
dc.description | Autor de correspondencia: Alicia Aranaz; 2004, American Society for Microbiology. All Rights Reserved. Financiación: Ramon y Cajal Program (Spanish Ministry of Science and Technology).Pproject AGL 2001-2029 of the Spanish Ministry of Science and Technology and by the Spanish Ministry of Agriculture, Fisheries and Food (MAPA). | |
dc.description.abstract | Spoligotyping is a major tool for molecular typing of Mycobacterium tuberculosis complex organisms. For epidemiological purposes, strains are considered clonal only when their spoligotyping patterns are identical. We report a change in the spoligotyping profiles of truly isogenic strains (a clinical isolate and a subculture derived in the laboratory) caused by deletion of a direct variable repeat. Without the information about the relationship between them, a link between these strains would have gone unnoticed. Evolutionary events should be taken into account in the interpretation of spoligotyping results and in the design of databases. | |
dc.description.department | Depto. de Sanidad Animal | |
dc.description.faculty | Fac. de Veterinaria | |
dc.description.refereed | TRUE | |
dc.description.sponsorship | Ministerio de Ciencia y Tecnología (España) | |
dc.description.sponsorship | Ministerio de Agricultura, Pesca y Alimentación (España) | |
dc.description.status | pub | |
dc.identifier.citation | Aranaz, A., Romero, B., Montero, N., Alvarez, J., Bezos, J., de Juan, L., Mateos, A., & Domínguez, L. (2004). Spoligotyping profile change caused by deletion of a direct variable repeat in a Mycobacterium tuberculosis isogenic laboratory strain. Journal of clinical microbiology, 42(11), 5388–5391. https://doi.org/10.1128/JCM.42.11.5388-5391.2004 | |
dc.identifier.doi | 10.1128/JCM.42.11.5388-5391.2004 | |
dc.identifier.essn | 1098-660X | |
dc.identifier.issn | 0095-1137 | |
dc.identifier.officialurl | https://doi.org/10.1128/JCM.42.11.5388-5391.2004 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14352/93502 | |
dc.issue.number | 11 | |
dc.journal.title | Journal of Clinical Microbiology | |
dc.language.iso | eng | |
dc.page.final | 5391 | |
dc.page.initial | 5388 | |
dc.publisher | American Society for Microbiology | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | en |
dc.rights.accessRights | open access | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.subject.cdu | 579.62 | |
dc.subject.ucm | Microbiología (Veterinaria) | |
dc.subject.unesco | 3109.05 Microbiología | |
dc.title | Spoligotyping Profile Change Caused by Deletion of a Direct Variable Repeat in a Mycobacterium tuberculosis Isogenic Laboratory Strain | |
dc.type | journal article | |
dc.type.hasVersion | VoR | |
dc.volume.number | 42 | |
dspace.entity.type | Publication | |
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relation.isAuthorOfPublication.latestForDiscovery | 4243d2aa-49ad-4afc-8924-8fbf5d0feae7 |
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