Datos de Investigación
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Item type: Item , Reverse delegated training and private inference via perfectly-secure quantum homomorphic encryption(2026) Ortega, Sergio A.; Martín-Delgado Alcántara, Miguel ÁngelQuantum machine learning in cloud environments requires protecting sensitive data while enabling remote computation. Here we demonstrate the first realistic implementations of a perfectly-secure quantum homomorphic encryption (QHE) scheme applied to quantum neural networks (QNN). Using efficient Clifford+T decomposition, we implement quantum convolutional neural networks for two complementary scenarios: (i) reverse delegated training, where encrypted data from multiple providers trains a user’s network via federated aggregation; (ii) private inference, where users process encrypted data with remote quantum networks. Moreover, analysis of server circuit privacy reveals probabilistic model protection through Pauli gate concealment. These results establish perfectly-secure QHE as a practical framework for multi-party quantum machine learning.Item type: Item , SQUWALS: a Szegedy QUantum WALks Simulator(2024) Ortega, Sergio A.; Martín-Delgado Alcántara, Miguel ÁngelSzegedy's quantum walk is an algorithm for quantizing a general Markov chain. It has plenty of applications such as many variants of optimizations. In order to check its properties in an error-free environment, it is important to have a classical simulator. However, the current simulation algorithms require a great deal of memory due to the particular formulation of this quantum walk. In this paper we propose a memory-saving algorithm that scales as (N2) with the size N of the graph. We provide additional procedures for simulating Szegedy's quantum walk over mixed states and also the Semiclassical Szegedy walk. With these techniques we have built a classical simulator in Python called SQUWALS. We show that our simulator scales as (N2) in both time and memory resources. This package provides some high-level applications for algorithms based on Szegedy's quantum walk, as for example the quantum PageRank.Item type: Item , Data: Mitigating magnesium reactivity in ceo2-containing waterborne coatings through zrcc and ldh surface pre-treatments(2026) Gómez Granados, Jonatan; Paulis, María; Mohedano Sánchez, Marta; Arrabal Durán, Raúl; Leiza, Jose Ramón; Vega Vega, Jesus ManuelOrganic coatings are used as one of the most effective strategies for the corrosion protection of metals. Nowadays, due to environmental regulations, the use of water-based coatings has become essential compared to solvent-based ones. However, their application to magnesium alloys remains largely unexplored due to their high reactivity with water. In the present work, a phosphate-functionalized waterborne binder is applied to AZ31B magnesium alloy. The surface has been modified by four different pre-treatments, respectively: (i) mechanical grinding, (ii) pickling, (iii) conventional conversion treatment, and (iv) a novel conversion treatment based on layered double hydroxides (LDH). The most promising pre-treatments are selected to explore their synergy with a biobased waterborne binder, containing CeO2 nanoparticles as a corrosion inhibitor. The morphology and composition of the different systems are studied, prior to and after corrosion tests in NaCl solution, by scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS). Results obtained by electrochemical impedance spectroscopy (EIS) in NaCl solution have revealed not only that LDH performs better than the conventional conversion treatment but also the synergy between LDH pre-treatment and CeO2 nanoparticles when two organic layers are used.Item type: Item , Effects of play-based interventions in Physical Education on emotional intelligence, self-concept, and assertiveness: an umbrella review(2026) Mínguez Rayo, Fernando; Navarro Asencio, EnriqueWhat are the effects of play-based interventions on emotional intelligence, self-concept and assertiveness in children and adolescents according to existing systematic reviews and meta-analyses in Physical Education? Play is one of the most relevant pedagogical resources in Physical Education due to its ability to promote the integral development of students. In addition to the physical and motor benefits, it facilitates social interaction, emotional experience and the creation of meaningful learning environments that contribute to socio-emotional development. Research indicates that playful activities support intrinsic motivation, creativity, and self-exploration, while promoting peer-to-peer communication and conflict resolution. In this context, emotional intelligence is configured as a fundamental competence, as it allows students to recognize, understand and regulate their emotions in situations of success and failure that are common in the game. In the same way, self-concept is a key element in the construction of the student's personal identity and can be strengthened through cooperative and participatory activities typical of play-based methodologies. Likewise, assertiveness is closely linked to the processes of social interaction that occur during playful dynamics. In recent years, various methodologies active in Physical Education have incorporated play as the axis of the teaching-learning process. These include Game-Based Learning, Teaching Games for Understanding, Sport Educational Model, Gamification and Cooperative Games. These proposals seek to generate meaningful learning experiences that integrate motor development with social and emotional development. However, although there are systematic reviews and meta-analyses on these methodologies, the available evidence is scattered. Therefore, it is pertinent to carry out an umbrella review that synthesizes these studies and offers a global vision of the effects of play-based interventions in Physical Education on emotional intelligence, self-concept and assertiveness.Item type: Item , Diagrama de especiación simulado del indio(2022) Gómez Martín, José MaríaDatos de porcentaje precipitado a dos concentraciones: 20 y 40 mg/LItem type: Item , Diagrama de especiación simulado del galio(2022) Gómez Martín, José MaríaDatos del diagrama de especiación del galio para 40 mg/L y 20 mg/LItem type: Item , Easily water-synthesisable iron-chloranilate frameworks as high energy and high-power cathodes for sustainable alkali-ion batteries(2025) Darby, James P.; Cliffe, Matthew J.; Garitaonandia, José S.; Grande-Fernández, Paloma; Morris, Andrew J.; Carretero-González, Javier; Castillo Martínez, Elisabet; Durán Egido, VíctorAchieving high battery performance from low-cost, easily synthesisable electrode materials is crucial for advancing energy storage technologies. Metal–organic frameworks (MOFs) combining inexpensive transition metals and organic ligands are promising candidates for high-capacity cathodes. Iron-chloranilate-water frameworks are herein reported to be produced in aqueous media under mild conditions. Removal of reticular water from known [Fe2(CAN)3(H2O)4] ⋅ 4H2O yields a new supramolecular metal–organic framework (SMOF), [Fe2(CAN)3(H2O)4]. Removing coordination water, a new 2D honeycomb-like MOF forms, Fe2(CAN)3, stable without counterions and solvent. This MOF adopts the unusual ABC layer-stacking, as determined using a combination of ab initio random structure searching, electron diffraction, and Rietveld refinement of powder XRD data. Magnetometry, Mossbauer and Raman spectroscopy confirm that all three [Fe2(CAN)3(H2O)x]⋅yH2O phases contain HS-Fe3+ and CAN2−, with magnetic ordering temperatures increasing (5→20 K) as the Fe−CAN connectivity increases. The SMOF and MOF show reversible (de)insertion of >4Li+/f.u. at average 2,59 V and 2,76 V vs Li+/Li, respectively. [Fe2(CAN)3] achieves 146 mAh/g at 1 C, thus specific energy (563 Wh/kg) and power (446 W/kg) in Li half-cells competitive with conventional LiFePO4 (~580 Wh/kg and ~450 W/kg). Beyond Li, [Fe2(CAN)3] delivers 394 Wh/kg and 421 Wh/kg, for Na and K half-cells respectively, becoming a competitive cathode for sustainable batteries.Item type: Item , Mechanistic insights and electrochemical performance of microwave-synthesized SnS for K-Ion batteries(2025) González Barrios, Marta María; Castillo Martínez, Elisabet; Garitaonandia, José S.; García Chamocho, Elena; Ávila Brande, David; Jesús Prado-Gonjal, Jesús; Prado Gonjal, Jesús de la PazItem type: Item , Regulación de la activación glial por inhibición de la recaptación de noradrenalina como tratamiento alternativo contra la neurodegeneración(2026) Muñoz Madrigal, José LuisEl presente conjunto de datos es producto del proyecto de investigación 'Regulación de la activación glial por inhibición de la recaptación de noradrenalina como tratamiento alternativo contra la neurodegeneración' (PID2021-123871OB-I00), financiado por el Ministerio de Ciencia e Innovación y desarrollado entre 2022 y 2025. Los datos recogen resultados de expresión génica obtenidos mediante qPCR en el contexto del estudio de la enfermedad de Alzheimer y otras patologías neurodegenerativas, con foco en el papel del sistema noradrenérgico y los procesos neuroinflamatorios. De este proyecto se derivan las publicaciones Gutiérrez, I. L., Yanes-Castilla, C., MacDowell, K. S., Caso, J. R., García-Bueno, B., Ulecia-Morón, C., … Madrigal, J. L. M. (2026). Reboxetine Treatment Reduces Hippocampal Gliosis in the P301S Tauopathy Mouse Model. ASN Neuro, 18(1). https://doi.org/10.1080/17590914.2026.2630485 (handle: https://hdl.handle.net/20.500.14352/133794 ) y Gutiérrez, I. L., Martín-Hernández, D., MacDowell, K. S., García-Bueno, B., Caso, J. R., Leza, J. C., & Madrigal, J. L. M. (2025). Cx3cl1 regulation of gliosis in neuroinflammatory and neuroprotective processes. International Journal of Molecular Sciences, 26(3), 959. https://doi.org/10.3390/ijms26030959 (handle: https://hdl.handle.net/20.500.14352/118191 ), ya depositadas en DOCTA.Item type: Item , Incidencia de las políticas migratorias de la UE en España: matrimonio y familia. Una visión crítica(El nuevo Pacto de Migración y Asilo a examen: Reflexiones desde la perspectiva de la descentralización territorial y de los derechos fundamentales, 2026) Martínez Rubio, Agustina; Ugartemendia Eceizabarrena, Juan Ignacio; Zelaia Galarza, Maite; Donaire Villa, Francisco Javier; Martinico, GiuseppeEl Reglamento (UE) 2024/1347, de 14 de mayo , que forma parte de un elenco de normas resultantes del nuevo Pacto sobre Inmigración y Asilo, diferencia, en su Preámbulo –considerando 19 –, entre las “relaciones familiares reales” y “los matrimonios o uniones contraídos con el único fin de que la persona interesada pueda entrar o residir en los Estados miembros”; de tal suerte que los beneficiarios de protección internacional, en el marco de este Reglamento, no podrán optar por el mantenimiento de la unidad familiar si, entre otras exigencias, existen indicios sobre la posible existencia de un matrimonio de conveniencia . Esta norma vuelve a incidir en una materia que comenzó a tratarse hace más de cinco lustros: la lucha contra los que se han denominado (entre otros apelativos) matrimonios fraudulentos, simulados o de conveniencia. De ahí que el objeto del presente trabajo sea mostrar y analizar, de un lado, cuál ha sido la “hoja de ruta” llevada a cabo en este campo tanto en España como en la Unión Europea desde una perspectiva cronológica; y, de otro, cómo han afectado a España las normas en materia de inmigración y las relativas el derecho a desplazarse y residir libremente en la UE, junto con las declaraciones del Consejo de la UE y la Comisión Europea. El estudio se divide en cuatro apartados. En ellos se expone, de forma ordenada, la doctrina de la Dirección General de Seguridad Jurídica y Fe Pública, las Resoluciones y/o Comunicaciones de la UE, y la normativa española y de la UE sobre este campo, mencionando algunas Resoluciones del Centro Directivo y sentencias de los tribunales, que, sin ánimo de ser exhaustivos, nos acercan al Derecho aplicado en la materia tratada.Item type: Item , Base de datos del proyecto EnDiversidad55+(2026) Sánchez Moreno, EstebanItem type: Item , Datos del artículo: Food anticipation, ghrelin, and anxiety in juvenile goldfish: evidence for a mesolimbic dopaminergic link?(2026) Herrera Castillo, Lisbeth Carolina; Azaoum-Salhi, Houda; Chivite-Alcalde, Mauro; Manuel Míguez, Jesús; Lozano Rebollo, Daniel; López Redondo, Jesús María; Pedro Ormeño, Nuria De; Isorna Alonso, EstherFood anticipatory activity (FAA) is described as a circadian increase in locomotor activity preceding a predictable meal. In goldfish, FAA has been shown to reflect an anxiety-like state associated with food expectation, which is not solely driven by circadian timing or passive metabolic signals related to prolonged fasting. This anxiogenic component is induced by ghrelin and reversed by ghrelin antagonism. Although ghrelin is known to regulate FAA and to engage dopaminergic reward circuits in mammals, the integration of ghrelin, dopamine, and anxiety within the context of FAA has not been established. Here, we investigated whether dopamine mediates ghrelin-induced anxiety during FAA in goldfish (Carassius auratus) using complementary behavioural, neurochemical, and transcriptional approaches. Pharmacological blockade of dopamine receptors during FAA revealed a prominent role of D2-like receptors in anxiety responses, although D1-like receptors are also involved. Consistently, ghrelin-induced anxiety-like behaviour was selectively reversed by D2 antagonism. Moreover, these D2-receptors were abundant in telencephalic regions associated with motivational processing. Furthermore, ghrelin increased dopamine and DOPAC levels in the telencephalic accumbens-like region and induced c-fos, tyrosine hydroxylase, and ghrelin receptors expression in the posterior tuberculum region, a key dopaminergic nucleus in teleost equivalent to the ventral tegmental area (VTA). Together, these results demonstrate that ghrelin recruits a dopaminergic pathway to modulate anticipatory anxiety during FAA in goldfish, with a predominant role of D2-like receptors. Our findings support the existence of a ghrelin–dopamine pathway in teleost that is functionally analogous to the mammalian ghrelin–VTA–dopamine circuit, suggesting an evolutionarily conserved mechanism linking metabolic signals, reward processing, and affective states.Item type: Item , Raw data for publication Exploring hollandite-type K y V x Ti8- xO16 (0.25 ≤ x ≤ 2) as electrode materials in potassium-ion batteries (KIBs)(2025) Nieto Simón, Juan Andrés; González Barrios, Marta María; Gómez Herrero, Adrián; Fernández-Díaz, María Teresa; Prado Gonjal, Jesús de la Paz; Castillo-Martínez, ElizabethItem type: Item , Publicaciones seriadas (Patrimonio Digital Complutense)(2026) Biblioteca de la Universidad Complutense de MadridComo parte de una institución dedicada a la enseñanza de la ciencia y a la investigación desde su fundación, la BUC cuenta con una importante colección de las principales revistas científicas europeas surgidas entre los siglos XVII-XIX. Por otro lado, conserva una importante colección de prensa. Algunos de los títulos más relevantes de ambos fondos se encuentran en esta colección digital, cuyos metadatos se ofrecen en este dataset.Item type: Item , Experimental data of the project FishFedEx (Effects of chronodisruption on energy homeostasis in goldfish)(2026) Saiz Aparicio, Nuria; Isorna Alonso, Esther; Herrera Castillo, Lisbeth Carolina; Delgado Saavedra, María Jesús; Ruiz-Jarabo De La Rocha, Ignacio; Pedro Ormeño, Nuria DeExperimental data of the project FishFedExItem type: Item , Public Trust in AI Enhanced News and the 'Audience AI Transparecy Trust Paradox': An Experimental Study on the Effects of AI Disclosure(2026) Parratt Fernández, Sonia; Mera Fernández, María Montserrat; Stalph, Florian; Thurman, NeilMedia organisations are increasingly using AI in news production. Disclosing this use promotes transparency and helps the audience better understand AI’s role in journalism. This study investigates the impact of AI disclosure on trust within the Spanish news ecosystem, where public trust in the media is notably low. Using a 3×3 between-subjects experiment (n=969), the research examines how different labelling conditions—no label, simple AI label, and AI label with an explanatory link—affect perceptions of AI-enhanced articles. Findings reveal an ‘audience AI transparency paradox’: while transparency is a valued principle, disclosure does not significantly alter trust during consumption. Instead, the news topic exerts a greater influence on perceived trustworthiness than the label type. A ‘reverse dynamic’ was also identified: participants with low AI familiarity showed increased trust when provided with ‘detail-on-demand’ links, whereas highly familiar users became more sceptical. The study concludes that simple labels are insufficient to bolster trust; it is suggested that newsrooms transition towards explainability —detailing how AI was used— in order to meaningfully engage audiences. These results offer critical insights for newsrooms navigating new ethical and reputational challenges.Item type: Item , Análisis de emociones en debate científico con alumnos de bachillerato(2023) Shamhood Soleimani, Safaa; Ezquerra Martínez, Ángel; Campillos Ladero, Rafael; Pamplona Roche, SoniaEste dataset contiene registros multimodales de 8 alumnos de bachillerato de un centro educativo de la Comunidad de Madrid que participaron en sesiones de debate científico durante el año 2024. Los datos fueron capturados con la plataforma iMotions v10 e integran de forma sincronizada tres fuentes de información: (1) expresiones faciales y emociones derivadas mediante Affectiva AFFDEX v2.0, incluyendo 13 emociones, 20 Action Units, pose de cabeza y métricas de parpadeo; (2) parámetros acústicos y emocionales de la voz, como frecuencia fundamental, intensidad, tasa de habla y estimaciones de emoción vocal; y (3) etiquetas de comportamiento anotadas manualmente, que clasifican cada intervención según su tipo e incluyen la transcripción de los turnos de habla. Los participantes fueron distribuidos en dos grupos: GrupoAlto (n=4) y Grupo Medio-Bajo (n=4). Cada archivo CSV corresponde a un único participante (~24.000 filas, 109 variables). Los datos han sido anonimizados y no contienen información sociodemográfica o biométrica identificable.Item type: Item , Cannabidiol-loaded-injectable depot formulation for the treatment of triple-negative breast cancer: design, development, in-vitro and in-ovo evaluation of its anticancer activity(International Journal of Pharmaceutics, 2026) Lozza, Irene; Hurtado-Marcos, Carolina; Montejo-Rubio, Consuelo; Martín Sabroso, Cristina; Fraguas Sánchez, Ana Isabel; Torres Suárez, Ana IsabelTriple-negative breast cancer (TNBC) is an invasive and difficult-to-treat carcinoma that represents 15–20 % of breast malignancies and is frequently diagnosed in younger women. Chemotherapy is the mainstay treatment approach. Cannabidiol (CBD), the main non-psychoactive cannabinoid, has shown a potential anticancer activity in TNBC, enhancing the effect of conventional antineoplastics. This research aims to develop in situ forming implants (ISFIs) as a long-acting depot formulation of CBD with potential application in TNBC. This formulation is intended to be administered in the tumor site during neoadjuvant chemotherapeutic regimens, allowing a controlled CBD release. ISFIs were elaborated with 100 mg of polycaprolactone (PCL) and 2.5 mg (2.5-CB-ISFI), 5 mg (5-CB-ISFI) or 10 mg (10-CB-ISFI) of CBD dissolved in 400 µL of NMP. All the formulations exhibited a controlled drug release for around two months. 10-CB-ISFI formulation with the highest CBD content and the most suitable CBD release profile was selected for biological studies. This formulation inhibited the proliferation and migration of MDA-MB-231 and 4T1 cells and exerted an antiangiogenic effect in ovo. Interestingly, the antiangiogenic activity of 10-CB-ISFI was higher compared with CBD in solution administered at the same concentration, showing vascular inhibition percentages of around 80 % and 60 %, respectively. Finally, this formulation reduced the growth of MDA-MB-231-derived tumors developed in the chorioallantoic membrane (CAM) model. The single administration of 10-CB-ISFI exhibited a similar antitumor efficacy to the daily administration of CBD in solution (≈60 % tumor growth inhibition). Therefore, the injectable depot formulation of CBD developed in this work showed a promising utility in TNBC treatment.Item type: Item , Experimental data of the project FishFedEx (Effects of microplastics in goldfish)(2026) Herrera Castillo, Lisbeth Carolina; Navajas-Jímenez, Nerea; Barany Ruiz, André; Isorna Alonso, Esther; Gómez Boronat, Miguel; Pedro Ormeño, Nuria DeExperimental data of of the project FishFedEx (Effects of microplastics in goldfish)Item type: Item , Thinking Tourism Professionally: A Cognitive-Semiotic Analysis of Multimodal ESP Tasks in AI-Poor Contexts(2026) Chaves Yuste, Beatriz; Silvera Roig, Marta; Calle Martínez, María Cristina