Efectos de la ventilación y la calidad de las compresiones torácicas durante la reanimación cardiopulmonar en un modelo animal pediátrico de parada cardiorrespiratoria asfíctica
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2022
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23/05/2022
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Universidad Complutense de Madrid
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Abstract
La calidad de las maniobras de reanimación cardiopulmonar (RCP), y entre ellas, la calidad de las compresiones torácicas (CT), el manejo de la vía aérea y la ventilación, pueden influir en la supervivencia de la parada cardiorrespiratoria (PCR), pero existen muy pocos estudios que hayan analizado su efecto en niños o en modelos animales pediátricos.OBJETIVOS1. En un modelo animal pediátrico de PCR asfíctica, estudiar el efecto de distintas características de la ventilación y de las compresiones torácicas sobre la recuperación de la circulación espontánea (RCE), la ventilación, oxigenación y hemodinámica: a. Comparar la ventilación con bolsa y mascarilla (VBM) coordinada con las CT con la ventilación no coordinada. b. Comparar las CT guiadas a tiempo real mediante un dispositivo, con las CT no guiadas. c. Comparar la intubación precoz con la VBM. d. Comparar la ventilación guiada por el volumen corriente (VGV) con la ventilación no guiada (VNG).2. Analizar la calidad de las CT y de la ventilación durante la reanimación cardiopulmonar...
High quality cardiopulmonary resuscitation (CPR) improves survival outcomes after cardiac arrest. There main components of high-quality CPR include chest compressions (CC) (minimize interruptions, provide compressions of adequate rate and depth, avoid leaning between compressions), airway management and ventilation. Nevertheless, there are few studies analyzing this effect in children or in pediatric animal models.OBJECTIVES:1. To study the effect of different ventilation and chest compression strategies on the recovery of spontaneous circulation (ROSC), ventilation, oxygenation and hemodynamics in a pediatric animal model of asphyxial cardiac arrest:a. To compare between synchronized and non-synchronized bag mask ventilation (BMV).b. To compare between guided and non-guided CC with a real-time feedback-device.c. To compare between early tracheal intubation (ETI) and BMV.d. To compare between tidal volume feedback (TVF) ventilation and non-guided or standard ventilation (SV).2. To analyze the quality of CC and ventilation during resuscitation...
High quality cardiopulmonary resuscitation (CPR) improves survival outcomes after cardiac arrest. There main components of high-quality CPR include chest compressions (CC) (minimize interruptions, provide compressions of adequate rate and depth, avoid leaning between compressions), airway management and ventilation. Nevertheless, there are few studies analyzing this effect in children or in pediatric animal models.OBJECTIVES:1. To study the effect of different ventilation and chest compression strategies on the recovery of spontaneous circulation (ROSC), ventilation, oxygenation and hemodynamics in a pediatric animal model of asphyxial cardiac arrest:a. To compare between synchronized and non-synchronized bag mask ventilation (BMV).b. To compare between guided and non-guided CC with a real-time feedback-device.c. To compare between early tracheal intubation (ETI) and BMV.d. To compare between tidal volume feedback (TVF) ventilation and non-guided or standard ventilation (SV).2. To analyze the quality of CC and ventilation during resuscitation...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Medicina, Departamento de Salud Pública y Maternoinfantil, leída el 23-05-2022