Palladium‐catalyzed hydroarylation of homopropargyl iodoindoles with concurrent alkyl and iodonium migrations
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2021
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Wiley-WCH GmbH
Citation
Martín-Mejías I, Aragoncillo C, Almendros P. Palladium-Catalyzed Hydroarylation of Homopropargyl Iodoindoles with Concurrent Alkyl and Iodonium Migrations. Adv. Synth. Catal. 2021, 363, 1449-1456.
Abstract
A selective palladium‐catalyzed C-arylation/carbocyclization/iodonium migration reaction sequence has been accomplished. Novel 2‐iodo‐1‐aryl‐9-H‐carbazoles are now easily available. As this result is contrary to the selectivity observed using gold catalysis, the formation of 2‐iodocarbazoles is noticeable, suggesting a metal‐controlled cyclization through chemo‐ and regioselective 1,2‐alkyl migration and 1,4‐iodonium migration.